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Platform
VasThera’s Drug Discovery Platform: “ENTER”
There are two natural enzymes that intracellularly control H2O2. One is the Peroxiredoxin (Prx) and the other is Glutathione
peroxidase (Gpx).
They are differentiated by coupling redox system, thioredoxin versus glutathione.
Our drug discovery platform called ENTER (ETP Networks for Thiol Enzyme Replacement)
comprises diverse small molecules mimicking Prx and Gpx activities.
These mimics can apply to various diseases, such as vascular, respiratory, cancer, and neurodegenerative disease,
depending on the status and expression of these enzymes.
They are differentiated by coupling redox system, thioredoxin versus glutathione.
Our drug discovery platform called ENTER (ETP Networks for Thiol Enzyme Replacement)
comprises diverse small molecules mimicking Prx and Gpx activities.
These mimics can apply to various diseases, such as vascular, respiratory, cancer, and neurodegenerative disease,
depending on the status and expression of these enzymes.
;)
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