R & D

In vivo study

Balloon Injury Model of Rat Carotid Artery

a carotid figure in the middle of the picture

After giving in-vessel injury using the balloon catheter, a test substance is administered.
The efficacy of test substances are evaluated by monitoring the thickness of carotid
arteries.

Mouse Carotid Artery Ligation Model

Left : Image of the partial ligation performed in mouse model

Right : Ultrasound image of the carotid arteries
(obtained by an Vevo imaging system)

Rat models of Pulmonary Arterial Hypertension

Left : Photographic image of heart in monocrotaline-induced PAH rat model

Right : Histologic image of pulmonary artery in monocrotaline-induced PAH rat model